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The story
The Yomiuri Shimbun reports that the diabetes drug Mounjaro is increasingly being used nationwide for weight loss rather than its approved purpose, with complaints reaching even Kumamoto Prefecture’s consumer affairs center. One woman who actually used it said she was frightened by how drastically her weight dropped, adding, “I don’t think I’ll use it again.” Doctors are warning of possible health damage from using the drug outside its intended purpose. On 5ch, actual users arguing “it’s fine if used correctly” clashed with those worried about long-term risks like osteoporosis and muscle loss, and the discussion expanded beyond Mounjaro to the risks of repurposing other diabetes drugs as well.
Published 9/15 (Tue) 7:30 AM
Yomiuri Shimbun Online
The use of the diabetes drug Mounjaro for weight-loss purposes has become a nationwide problem. In Kumamoto Prefecture alone, two complaints have been filed with the prefectural consumer affairs center, and Dr. Ken Doi of Doi Internal Medicine Clinic (Minami Ward, Kumamoto City) warns that “using it for a purpose other than intended can cause health damage.” A woman who has actually used the drug spoke with the Yomiuri Shimbun. (By Yuka Tatehata and Yukari Nakamura)
Source: news.yahoo.co.jp / Original article here
What people said
Mounjaro's an injection, not something you drink.
I use it too and I don't feel sick at all.
Your appetite drops, sure.
But as long as you just eat a bit less at each of your three meals, you're totally fine.
If you skip meals entirely or only eat once a day, yeah, you'll look pale.
Anyway, ¥4,000 a pen is insanely cheap.
There's an osteoporosis risk. You'll definitely regret it once you're old.
Diabetic patients get all sorts of checkups, but do you really think doctors handing out Mounjaro [off-label] bother with any of that?
In the US, a lot of drug-related deaths aren't from narcotics — they're accidents from doctors carelessly prescribing meds.
For diabetics, it's worth the risk if it's lower than the risk of letting their diabetes get worse. That doesn't mean "diabetics use it, so it must be risk-free."
lolololol
That's true for bodybuilders, but just living a normal life builds some muscle, so unless you're bedridden you'll be fine.
If you don't eat, fat goes down too. That's just obvious.
Muscle keeps declining every year, that's exactly why elderly people who don't do anything eventually can't move anymore, you know?
That's just aging.
If you do nothing, your muscle keeps declining for more than half your life. You wouldn't call that "building muscle just by living normally," would you?
Even just walking builds some muscle. Well, if it bothers you, go do some crunches or squats.
"More than half" is an exaggeration, but once you're past 60 it really is downhill without exercise. That's just how the human body works, can't be helped.
That one makes you prone to dehydration, so you have to keep drinking water constantly.
Guess you don't know about the side effect where it causes genital infections (excess sugar spilling into the urine irritates the area).
That's how I ended up with a nice clean head too (i.e., went bald).
Chemo is absolutely brutal. So many people would rather die of cancer than go through the suffering of chemo.
Mounjaro, on the other hand, stimulates the brain's satiety center, so you stay feeling full the whole time — apparently really easy.
That's what some influencer said, anyway.
So having a wife who's 155cm and 38kg makes me a winner, right?
Just make sure you stay healthy yourself — if you get too big, your wife won't be able to take care of you when the time comes.
That's way too skinny lol
Just amputate both legs, I guess.
Isn't that because the actual cause of the diabetes is that your body just isn't producing insulin?
Well obviously exercising to burn off fat is safer.
And how exactly are you supposed to do that?
Apparently that category of obesity drug basically requires adult diapers — you get no urge to go, and greasy, fat-laden stool just leaks out on its own.
Background and key points of this discussion
Mounjaro (tirzepatide) is a GLP-1/GIP receptor agonist approved in Japan for treating type 2 diabetes and obesity. It’s meant to be prescribed by a doctor for specific approved conditions, but off-label use for cosmetic weight loss has spread nationwide, prompting complaints even to Kumamoto Prefecture’s Consumer Affairs Center — the backdrop for this article. On the thread, actual users insisting “it’s fine if you use it correctly” clashed with cautious voices warning of risks like osteoporosis and muscle loss, and no consensus was reached. One commonly misunderstood point: losing weight doesn’t cure diabetes itself — without fixing the underlying insulin problem, it isn’t a real treatment. Other diabetes drugs like Forxiga are likewise being repurposed for weight loss, with risks such as dehydration and other side effects reported, suggesting this isn’t a Mounjaro-only issue but part of a broader pattern of diabetes medications being used off-label.
*This article is excerpted and summarized from the 5ch (News Speed+) thread “Woman Who Used Diabetes Drug Mounjaro for Weight Loss Got Scared by Drastic Weight Drop: ‘I Don’t Think I’ll Use It Again’.”
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